TKTKPLUS: A fentanyl vaccine is about to get its first major test. View in browser | Your newsletter preferences12.08.25 The Longest Solar Eclipse for 100 Years Is Coming. Don’t Miss It BY JORGE GARAY | 1-MINUTE READNASA has announced when the longest total solar eclipse of the century will occur—and you won’t have to wait long. Here’s what you should know. A Fentanyl Vaccine Is About to Get Its First Major Test BY EMILY MULLIN | 5-MINUTE READARMR Sciences of New York is trialing a vaccine in the Netherlands to protect against fentanyl-related overdose and death. Why Tehran Is Running Out of Water BY YEON-WOO CHOI AND ELFATIH A. B. ELTAHIR | 3-MINUTE READBecause of shifting storms and sweltering summers, Iran’s capital faces a future “Day Zero” when the taps run dry. A Startup Says It Has Found a Hidden Source of Geothermal Energy BY MOLLY TAFT | 4-MINUTE READZanskar uses AI to identify hidden geothermal systems—and claims it has found one that could fuel a power plant, the first such discovery by industry in decades. This AI Model Can Intuit How the Physical World Works BY ANIL ANANTHASWAMY | 5-MINUTE READThe V-JEPA system uses ordinary videos to understand the physics of the real world. ADVERTISEMENT Can AI Look at Your Retina and Diagnose Alzheimer’s? Eric Topol Hopes So BY MARAH EAKIN | 3-MINUTE READThe author of Super Agers believes AI could bring big changes to the world of medicine. Want This Hearing Aid? Well, Who Do You Know? BY STEVEN LEVY | 13-MINUTE READAI-powered startup Fortell has become a secret handshake for the privileged hearing-impaired crowd who swear by the product. Now, it wants to be in your ears. Your Data Might Determine How Much You Pay for Eggs BY MADDY VARNER | 3-MINUTE READA newly enacted New York law requires retailers to say whether your data influences the price of basic goods like a dozen eggs or toilet paper, but not how. An AI Dark Horse Is Rewriting the Rules of Game Design BY WILL KNIGHT | 3-MINUTE READThe Chinese video game giant Tencent is now building some of the world’s best 3D AI models. This could have implications far outside gaming. As Key Talent Abandons Apple, Meet the New Generation of Leaders Taking On the Old Guard BY SOPHIE CHARARA | 8-MINUTE READWith “hardware guy” John Ternus as frontrunner for the next CEO, can Apple overtake its ex-employees at OpenAI and Meta? ADVERTISEMENT You’re up to date! Was this newsletter forwarded to you? Sign up here. Plus, browse more newsletters from WIRED. You’re receiving this email because you signed up for the Science newsletter from WIRED. Manage your preferences | View our Privacy Policy | Unsubscribe Have questions or comments? Send us a message. Need help? Contact us. Copyright © Condé Nast {date(“yyyy”)}. One World Trade Center, New York, NY 10007. All rights reserved.
